CA25105 - Precision Detection and Prevention of Psychosis (PDPP) Network (PDPP-Network)

Τhe main objective of the PDPP Network Action is to coordinate a pan-European interdisciplinary effort to promote personalised preventive approaches for patients at clinical high-risk for psychoses (CHR-P), as psychoses are the most severe and costly group of psychiatric disorders. Covering epidemiology, screening, diagnosis, personalised prognosis and intervention, PDPP Network develop the urgently needed European interaction between scientists, clinicians, regulatory authorities, advocacy groups, and SMEs in the field of psychiatric prevention. This is aligned with the EU Commission strategy 2024 promoting mental health with adequate and effective prevention, access to high quality and affordable mental health care and treatment. Due to the early onset of psychosis, there is also an urgent need of close European cooperations between experts in child and adolescent psychiatry, and adult psychiatry; this will take top priority in the PDPP Network. The Action addresses that indicated prevention can prevent psychosis or significantly ameliorate its course, and that the rising development and application of artifical intelligence in prevention, diagnosis and risk-adapted therapy of CHR-P leads to the development of innovative therapeutic options. The Action is organised into eight Working Groups (WG) on the standardisation of diagnostic procedures, the development of an integrative CHR-P assessment and individual risk profiles, the personalised treatment of patients with identification of epidemiological heterogeneity and patient-centred support management, flanked by two horizontal WG that provide cross-cutting activities relevant to the objectives of these WGs: artificial intelligence and ethics/stigma concepts. This will result in the first-time implementation of standards of European CHR-P service.