Scientific Publications
Új exodus
Bioactive Compounds in Plant Foods - Health Effects and Perspectives for the Food Industry
A Guide to the Sensory Evaluation of the Texture of Hard and Semi-hard Ewes' Milk Cheeses
Leuven Proceedings - New Ligh Alloys Part A
Environment in the EU at the Turn of the Century - Appendix to the Summary - Facts and Findings per Environmental Issue
Work Package 4
1992
Schlussbericht der untergruppe "radiosonden"
Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer
- Author(s): Sersa G., Teissie J., Cemazar M., Signori E., Kamensek, U., Marshall G., Miklavcic D
- Publisher(s): Springer
- http://link.springer.com/article/10.1007%2Fs00262-015-1724-2
Electroporation is a platform technology for drug and gene delivery. When applied to cell in vitro or tissues in vivo, it leads to an increase in membrane permeability for molecules which otherwise cannot enter the cell. The therapeutic effectiveness of delivered chemotherapeutics or nucleic acids depends greatly on their successful and efficient delivery to the target tissue. Therefore, the understanding of different principles of drug and gene delivery is necessary and needs to be taken into account according to the specificity of their delivery to tumors and/or normal tissues.