CA25149 - Reliability of Spectroscopy and Imaging based Photonic Technologies for Biomedical Applications (Reliability4Photonics)

Photonic technologies including vibrational spectroscopy and nonlinear optical imaging as label-free approaches have shown unique advantages to investigate biological samples like cells, tissues, biofluid, bacteria, etc. Combined with data analysis and computational facilities, they have brought vast possibilities to deeper understanding diseases and biological processes and to gain unique insights in metabolisms, pathology, therapy, prognosis, precision medicine, and drug development. Broader clinical and biomedical applications of these technologies are, however, hindered by the lack of standardization and harmonization in both measurement and data analysis. This Action aims for community efforts with following stated goals to  improve the situation.

·         To establish standard protocols for photonic measurements including Raman, IR, and nonlinear optical imaging in clinical and biomedical applications.

·         To establish standard pipelines of data analysis and data quality assessment for each photonic modality.

·         To establish standard structures and information to be published and included as metadata for clearer data description and better reusability.

·         To develop platforms for data management that will support the construction and maintenance of standard databases, and more importantly, smoother European wide cooperations and community studies.

·         To develop a European-wide multidisciplinary network of researchers including pathologists, microbiologists, physicists, chemists, microbiologists, engineers, and big data scientists and align them with clinical applications towards a critical mass of participants to establish precision diagnostic requirements and address challenges in healthcare applications.

·         To push forward the photonic technologies into broader clinical and biomedical applications.