Description
The sigma-1 receptor (S1R) is a ligand-regulated endoplasmic reticulum chaperone protein and a target for innovative compounds for the treatment of neurodegenerative and inflammatory diseases, cancers and pain diseases. The SIGMA-1 EUROPE network will bring together disciplines and expertises across Europe to advance the exploration and identification of the role of S1R in physiology and pathologies, to design innovative S1R ligands for cellular biology and medicine, and ultimately to train Young Reserachers and Innovators to revise current views of the diseases, to think out-of-the-box and explore novel and innovative S1R-based therapeutic opportunities.
Action keywords
Pharmacology - Drug development - Translational training - Cytoprotection - Pain
Management Committee
| Country | MC Member |
|---|---|
| Austria | |
| Austria | |
| Belgium | |
| Bosnia and Herzegovina | |
| Croatia | |
| Cyprus | |
| Cyprus | |
| Estonia | |
| Estonia | |
| France | |
| France | |
| Georgia | |
| Georgia | |
| Germany | |
| Germany | |
| Greece | |
| Greece | |
| Hungary | |
| Hungary | |
| Israel | |
| Italy | |
| Italy | |
| Latvia | |
| North Macedonia | |
| North Macedonia | |
| Poland | |
| Portugal | |
| Portugal | |
| Romania | |
| Romania | |
| Serbia | |
| Serbia | |
| Slovakia | |
| Slovenia | |
| Slovenia | |
| Spain | |
| Spain | |
| Sweden | |
| Switzerland | |
| Türkiye |
Main Contacts
Action Contacts
COST Staff
Leadership
| Role | Leader |
|---|---|
| Action Chair | |
| Action Vice-Chair |
Working Groups
| Number | Title | Leader |
|---|---|---|
| 1 | Drug design, modelling, radiotracers | TBA |
| 2 | Sigma-1 receptors in neurodegenerative, inflammatory, cancer and cardiometabolic diseases | TBA |
| 3 | Establishment of SOPs for in-vitro/in-vivo models to assess sigma-1 receptor ligands | TBA |
| 4 | Industry strategies requirements for drug development | TBA |
| 5 | Dissemination, Communication and Outreach | TBA |
Express your interest to join any of the working groups by applying below.
It is required to have an e-COST profile to submit your application. If needed, create it first and then click 'Apply'.
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