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CMST COST Action CM1003
Biological oxidation reactions - mechanisms and design of new catalysts

Biological oxidation reactions utilizing dioxygen, superoxide, hydrogen peroxide, or water as oxidants are the most common metal catalyzed reactions in in biology. Despite the intense study of such reactions, key knowledge remains to be established in many cases - e.g. the nature of the active oxidant and the molecular mechanism of oxidation. In this Action, scientists are studying not only the mechanisms of important oxidation reactions via biophysical studies on relevant metalloenzymes and/or model complexes, as well as by computational modelling, but are also designing new catalysts for such reactions. Two classes of potential new catalysts are investigated: (i) “artificial metalloproteins” , i.e. small metalloproteins, produced primarily by de novo synthesis, that contain active sites that are direct mimics of those found in metalloenzymes (ii)coordination complexes that reproduce essential features of enzyme active sites.

(Descriptions are provided by the Actions directly via e-COST.)

General Information*

Chair of the Action:


Vice Chair of the Action:

Prof Angelina LOMBARDI (IT)

Science officer of the Action:

Dr Lucia FORZI

Administrative officer of the Action:

Ms Svetlana VOINOVA


Action Fact Sheet

Download AFS as .RTF

Memorandum of Understanding

Download MoU as PDF

Progress Report

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Download Poster as PDF


Last updated: 02 May 2011 top of page