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CMST COST Action CM1106
Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells

Descriptions are provided by the Actions directly via e-COST.

This COST Action aims to unite researchers with expertise in rational drug design and the medicinal chemistry of synthetic and natural compounds with biomedical investigators dedicated to the understanding the mechanisms governing drug resistance in cancer stem cells. Cancer stem cells (CSC)  are a subpopulation of cells within tumors that exhibit enhanced tumor-initiating attributes and are a major contributing factor to current cancer therapy failure. The CSC phenotypic state comprises distinct molecular and functional differences that underpin resistance to current treatments and the unique ability spread and to seed new tumors throughout the body. This insight necessitates an entirely new approach to cancer drug development to effectively target tumor CSCs. Through exchange of information, experience and expertise, researcher mobility and fostering new collaboration between chemistry and biology groups, the Action endeavours to develop new, effective methods for identifying novel compounds and drug candidates that target drug-resistant cancer stem cells.


General Information*

Chair of the Action:

Prof Daniele PASSARELLA (IT)

Vice Chair of the Action:

Dr Marija BALIC (AT)

Science officer of the Action:

Dr Lucia FORZI

Administrative officer of the Action:

Ms Svetlana VOINOVA

Downloads*

Action Fact Sheet

Download AFS as .RTF

Memorandum of Understanding

Download MoU as PDF

Progress Report

Download Progress Report as PDF

Poster

Download Poster as PDF

Websites*

Action website:

www.stemchem.org

Domain website:

http://www.cost.eu/cmst

* content provided by e-COST.
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Last updated: 03 December 2011 top of page

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