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BMBS COST Action BM1208
European Network for Human Congenital Imprinting Disorders

Imprinting disorders (IDs) are a group of rare congenital diseases affecting growth, development and metabolism with a lifelong impact on patients' quality of life. Despite their common underlying (epi)genetic aetiologies, IDs are usually studied separately by small groups working in isolation, and the basic pathogenesis and long term clinical consequences of IDs remain largely unknown. Efforts to elucidate the aetiology of IDs are currently fragmented across Europe and standardisation of diagnostic and clinical management is lacking. This Action will, for the first time, draw together researchers of all eight known human IDs in an interdisciplinary pan-European Network for Human Congenital IDs, working to advance understanding of the pathophysiology with the major aim of translating this knowledge to improvement of diagnostic and clinical management for the benefit of the patients and their families. The Action will harmonise a common ID classification system, develop guidelines for treatment through consensus, create standard operation procedures (SOPs) for diagnosis based on best current practice, coordinate databases held in different countries to make them compatible and useful as a springboard for collective research initiatives, identify new imprinting disorders through collaborative effort, educate researchers and stimulate translational exchange. The ID network will join forces and complement studies to reduce health care costs and increase the life quality of patients.

(Descriptions are provided by the Actions directly via e-COST.)

General Information*

Chair of the Action:

Prof Thomas EGGERMANN (DE)

Vice Chair of the Action:

Prof Irène NETCHINE (FR)

Science officer of the Action:

Dr Federica ORTELLI

Administrative officer of the Action:

Ms Jeannette NCHUNG ORU


Action Fact Sheet

Download AFS as .RTF

Memorandum of Understanding

Download MoU as PDF

Second Progress Report

Download Second Progress Report as PDF

Final Achievement Report

Download Final Achievement Report as PDF


* content provided by e-COST.
Data is synchronised once per night.


Last updated: 24 November 2012 top of page